Editorial: Tumor Heterogeneity
نویسندگان
چکیده
منابع مشابه
Human Cancer Modeling: Recapitulating Tumor Heterogeneity Towards Personalized Medicine
Despite diagnostic, preventive and therapeutic advances, growing incidence of cancer and high rate of mortality among patients affected by specific cancer types indicate current clinical measures are not ideally useful in eradicating cancer. Chemoresistance and subsequent disease relapse are believed to be mainly driven by the cell-molecular heterogeneity of human tumors that necessitates perso...
متن کاملHuman Cancer Modeling: Recapitulating Tumor Heterogeneity Towards Personalized Medicine
Despite diagnostic, preventive and therapeutic advances, growing incidence of cancer and high rate of mortality among patients affected by specific cancer types indicate current clinical measures are not ideally useful in eradicating cancer. Chemoresistance and subsequent disease relapse are believed to be mainly driven by the cell-molecular heterogeneity of human tumors that necessitates perso...
متن کاملTumor heterogeneity.
In 1977, Dan Dexter and I, with colleagues at Roger Williams General Hospital, submitted a manuscript to Cancer Research in which we reported the isolation of four distinct tumor subpopu lations from a single, spontaneously arising mouse mammary cancer. We speculated that these subpopulations were evidence for intraneoplastic heterogeneity and that heterogeneity was a general phenomenon, knowle...
متن کاملTumor cell heterogeneity.
The paper deals with the analysis of literary data on the tumor cell heterogeneity. Phenotypic, genetic and epigenetic mechanisms of heterogeneity are considered. The heterogeneity of metastasis is considered too. The importance for the biology of populations of tumor cells and the sensitivity of tumors to therapeutic treatment are discussed.
متن کاملDifferentiation of active tumor from edematous regions of glioblastoma multiform tumor in diffusion MR images using heterogeneity analysis method
Background: Due to intrinsic heterogeneity of cellular distribution and density within diffusion weighted images (DWI) of glioblastoma multiform (GBM) tumors, differentiation of active tumor and peri-tumoral edema regions within these tumors is challenging. The aim of this paper was to take advantage of the differences among heterogeneity of active tumor and edematous regions within the gliobla...
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ژورنال
عنوان ژورنال: Frontiers in Medicine
سال: 2019
ISSN: 2296-858X
DOI: 10.3389/fmed.2019.00156